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※ Genome Enzyme Mining |
※ Custom Enzyme Production |
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■ Bioinformatics |
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■ Selection of expression hosts |
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■ cDNA library construction |
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■ Expression optimization |
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■ Genomic DNA preparation |
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■ Enzyme purification & formulation |
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■ Enzyme cloning |
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■ Formulation from 5L>1000L |
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■ Assay development and library
screening |
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※ Custom Development of Enzyme Libraries |
※ Bionsynthesis of Chiral Compounds and Drug Metabolites |
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■ Genome mining and library design |
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■ Enzyme and microbial screening |
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■ Enzyme cloning and expression |
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■ Synthesis of chiral compounds |
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■ Protein engineering and |
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■ Synthesis of drug metabolites |
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■ directed evolution |
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■ Biotransformations scaling up |
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■ Enzyme immobilization |
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